Graduate

CHEM 200A Advanced Biochemistry: Biophysical Methods

An introduction to the theory, principles, and practical application of biophysical methods to the study of biomolecules, especially proteins and nucleic acids. Emphasis on spectroscopic techniques. Topics include magnetic resonance, optical spectroscopy, fast reaction techniques, crystallography, and mass spectrometry.

Credits

5

CHEM 200B Advanced Biochemistry: Macromolecular Structure and Function

A detailed discussion of nucleic acid and protein chemistry, ranging from the structure, thermodynamics, and folding to the relationship between structure and function, and encompassing the methods used to determine such information.

Credits

5

CHEM 200C Advanced Biochemistry: Enzyme Mechanisms and Kinetics

A study of enzyme kinetics, mechanisms, and factors involved in enzymic catalysis. Lecture: 3-1/2 hours.

Credits

5

CHEM 222 Career Success in Industrial Science/ Engineering

Provides skills for the transition from academia into industrial research careers, addressing presentation skills, project prioritization, teamwork, salary-benefit expectations, intellectual property, performance reviews, Myers-Briggs profiles, and career planning. Participant teams will analyze the commercialization of a technical innovation.

Credits

2

Requirements

Enrollment is restricted to Physical and Biological Sciences and School of Engineering graduate students who have completed one consecutive year. Undergraduates may enroll on a space available basis by permission of instructor.

CHEM 230 Grant Writing in Biomedical Research

Introduces the fundamentals of grant writing in biomedical research, including best practices for presentation of data and communication of research findings. Students write and peer-edit most components of the NIH Ruth L. Kirschstein F31 predoctoral fellowship. Course is designed for students in their second year or later of graduate study.

Credits

5

Requirements

Enrollment is restricted to graduate students.

CHEM 234 Bioinorganic Chemistry

The role played by transition metals in biological systems is discussed through application of the principles of coordination chemistry and inorganic spectroscopy. Topics include metalloproteins involved in oxygen binding, iron storage, biological redox reactions, and nitrogen fixation, as well as metal complexes of nucleic acids. Lecture: 4 hours.

Credits

5

Requirements

Prerequisite(s): CHEM 151A, CHEM 151L, CHEM 163A, and BIOC 100A; or graduate students.

CHEM 238 Topics in Biophysical Chemistry

A discussion of the application of selected topics in biophysical chemistry to contemporary problems in biochemistry and molecular biology. Lecture: 3-1/2 hours.

Credits

5

CHEM 242A Modern Physical Organic Chemistry

Covers molecular structure and bonding, strain, and non-covalent binding forces. Other topics include acid-base chemistry, kinetics, thermodynamics, catalysis, organic reactions and mechanism, and quantum mechanical approaches to the analysis of organic molecules.

Credits

5

Requirements

Enrollment is restricted to seniors who have taken CHEM 143, and graduate students.

CHEM 242B Modern Synthetic Methods in Organic Chemistry

Presents concepts in bond formation, conformation, selectivity, and stereocontrol in modern organic synthesis. Focuses on understanding reaction mechanisms. Culminates with strategy in designing multi-step synthesis of complex targets.

Credits

5

Requirements

Enrollment is restricted to seniors who have taken CHEM 143, and graduate students.

CHEM 242C Spectroscopy and Applied Analytical Methods

Presents strategies in organic structure elucidation, including nuclear magnetic resonance (NMR) and mass spectrometry. Provides theory and practical elements of structure elucidation and modern analytical methods for organic molecules.

Credits

5

Requirements

Enrollment is restricted to seniors who have taken CHEM 143, and graduate students.

CHEM 244 Organic Free Radical Chemistry

Explores organic free radicals. Fundamental principles in physical chemistry provide an understanding of free-radical transformations in organic synthesis, polymerization, and some examples of free radicals in biology. For students who have a firm grounding in organic chemistry.

Credits

5

Requirements

Enrollment is restricted to graduate students.

CHEM 247 Using DFT Computational Methods to Study Molecular Structure and Reactivity

This course is fully hands-on, highly interactive, and project-based. Students receive extensive training on the DFT program Gaussian and are then offered the opportunity to deepen their knowledge, tailored to their specific research projects. Students have the option to bring in their own molecules of interest from their research laboratories.

Credits

5

Requirements

Enrollment is restricted to graduate students.

CHEM 256A Advanced Topics in Inorganic Chemistry

Advanced topics in inorganic chemistry are presented. Topics covered vary from year to year, and are announced in advance. Possible topics include A) organometallic chemistry; B) structural methods in inorganic chemistry; C) solid-state chemistry.

Credits

5

Requirements

Enrollment is restricted to graduate students or previous enrollment in CHEM 151A, CHEM 151L, and CHEM 146B.

CHEM 256B Advanced Topics in Inorganic Chemistry

Advanced topics in inorganic chemistry are presented. Topics covered vary from year to year, and are announced in advance. Possible topics include A) organometallic chemistry; B) structural methods in inorganic chemistry; C) solid-state chemistry.

Credits

5

Requirements

Enrollment is restricted to graduate students or previous enrollment in CHEM 151A, CHEM 151L, and CHEM 146B.

CHEM 256C Advanced Topics in Inorganic Chemistry

Advanced topics in inorganic chemistry are presented. Topics covered vary from year to year, and are announced in advance. Possible topics include A) organometallic chemistry; B) structural methods in inorganic chemistry; C) solid-state chemistry.

Credits

5

Requirements

Enrollment is restricted to graduate students or previous enrollment in CHEM 151A, CHEM 151L, and CHEM 146B.

CHEM 256D X-ray Crystallography

Course in chemical crystallography focuses on the needs of small-molecule, single-crystal diffraction studies. Includes diffraction theory, space-group analysis, data collection, structure solution, and refinement. Practical component: use of diffraction equipment and solution/refinement software.

Credits

5

Requirements

Enrollment is restricted to graduate students and seniors who have taken CHEM 151A, CHEM 151L, and CHEM 163A.

CHEM 261 Foundations of Spectroscopy

The basic theory of time-dependent processes is covered at an advanced level. The interaction of electromagnetic radiation and matter is described using both semiclassical and quantum field formulations. A variety of modern spectroscopic techniques are discussed both in terms of the basic processes and their use in the elucidation of chemical structure and dynamics.

Credits

5

Requirements

Enrollment is restricted to chemistry graduate students or previous enrollment in CHEM 163A.

CHEM 262 Statistical Mechanics

Theory and concepts of statistical mechanics with applications to ideal gases, condensed systems, phase transition, and non-equilibrium thermodynamics. Lecture: 3-1/2 hours.

Credits

5

Requirements

Enrollment is restricted to chemistry graduate students or previous enrollment in CHEM 163A.

CHEM 263 Quantum Mechanics

A rigorous introductory course: the Schrödinger equation, operator formalism, matrix mechanics, angular momentum, and spin. Perturbation and other approximate methods. Applications to atomic and molecular problems. Lecture: 3-1/2 hours.

Credits

5

Requirements

Enrollment is restricted to chemistry graduate students or previous enrollment in CHEM 163A, PHYS 116A, and PHYS 116C.

CHEM 264 Computational Materials

Introduction of quantum mechanical simulations of materials at the atomistic level. This includes introduction of solid-state electronic structure formulated with density functional theory and plane-wave basis, calculations of spectroscopic and transport properties for solids and condensed phases from first-principles. Basic calculations of electronic structure, lattice dynamics with phonon dispersion and dielectric properties, treatment of electron correlation for open-shell systems with linear and non-linear magnetism. Advanced topics include calculations of excited-state spectroscopy with many-body interaction, ab-initio molecular dynamics, Wannier function and topological properties, and electron-phonon coupling for superconductivity and carrier transport. 

Credits

5

Requirements

Prerequisite(s): Enrollment is restricted to graduate students; undergraduates who have completed PHYS 102 or CHEM 163A may enroll.

CHEM 265 Computer Simulation in Statistical Mechanics

A detailed introduction of the use of computer simulation methods in physical and biophysical chemistry. Includes review of thermodynamics and statistical mechanics, molecular mechanics, molecular dynamics, and Monte-Carlo methods. Applications to liquid structure, reaction dynamics, and protein dynamics.

Credits

5

CHEM 268 Solid State and Materials Chemistry

Topics include synthesis of solid-state materials and their characterization using experimental techniques: XRD, TEM spectroscopy, NMR, and their applications in technologies. Emphasis on new materials, e.g., polymer, biopolymers, nanomaterials, organic/inorganic composites, ceramics, superconductors, electronic, magnetic, and opto-electronic materials.

Credits

5

Requirements

Enrollment is restricted to chemistry graduate students or students previously enrolled in CHEM 163A and CHEM 163B.

CHEM 269 Electrochemistry

Designed to introduce basic principles and applications of electrochemistry to students at upper undergraduate and lower graduate levels in various fields including analytical, physical, and materials chemistry.

Credits

5

Requirements

Enrollment is restricted to seniors and graduate students.

CHEM 271 Chemical Biology

Methods and techniques for the field of chemical biology. Brings together methods in chemistry, biochemistry, and genetics to study the interaction of small molecules with biological systems. Students cannot receive credit for this course and CHEM 171.

Credits

5

Requirements

Enrollment is restricted to chemistry graduate students.

CHEM 272 Mass Spectrometry: Fundamentals and Applications

Lecture and lab course introducing graduate students to mass spectrometry. Begins with the basic framework and concepts in mass spectrometry to break down modern instrumentation to build toward utilizing modern biomedical applications of the technology. Course focuses on biological molecules (amino acids to proteins). Interpretation of organic mass spectra is only be briefly covered. Provides students with the necessary framework to design and execute their own research-based mass spectrometry experiments. Two weeks are dedicated to hands-on experiments using modern mass spectrometers and preparing short technical notes based on the Journal of the American Society for Mass Spectrometry (JASMS) to report findings from laboratory base experiments.

Credits

5

Requirements

Enrollment is restricted to graduate students.

CHEM 274 Proseminar in Synthetic and Polymer Chemistry

Weekly meetings devoted to study of synthetic organic chemistry and controlled polymer design for applications in nanotechnology. Topics drawn from current literature and research interests of participants.

Credits

5

Repeatable for credit

Yes

Quarter offered

Spring

CHEM 275 Proseminar in Biological Inorganic Chemistry

Weekly meetings devoted to biological inorganic chemistry and biochemistry. Topics are drawn from current literature. Papers and reviews are discussed, and participants give short seminars on their research interests.

Credits

5

Repeatable for credit

Yes

CHEM 280 Proseminar in Materials Chemistry

Weekly meetings devoted to materials and inorganic research. Topics are drawn from current literature. Papers and reviews are discussed. Participants also give short seminars on topics of their research interests.

Credits

5

Repeatable for credit

Yes

CHEM 282 Proseminar: Synthetic Methods

Weekly meetings devoted to the study of asymmetric and/or enantio-selective synthesis of optically active organic compounds of biological and medicinal significance. Topics drawn from the current literature and the research interests of the participants.

Credits

5

Requirements

Enrollment is restricted to graduate students.

Repeatable for credit

Yes

CHEM 284 Proseminar in Synthetic Organic Chemistry

Weekly meetings devoted to the study of synthetic organic chemistry. Topics drawn from the current literature and the research interests of the participants.

Credits

5

Requirements

Enrollment is restricted to graduate students.

Repeatable for credit

Yes

CHEM 285 Proseminar: Photobiochemistry and Photobiology

A detailed study of molecular mechanisms of light energy conversion and light-signal transduction processes in biological systems. Student participation in critical discussion of current literature examples are emphasized. Two-hour lecture and two-hour seminar weekly.

Credits

5

Requirements

Enrollment is restricted to graduate students.

Repeatable for credit

Yes

CHEM 286 Proseminar in Natural Products Chemistry

Weekly meetings devoted to the study of natural products. Topics drawn from the current literature and research interests of the participants.

Credits

5

Requirements

Enrollment is restricted to graduate students.

Repeatable for credit

Yes

CHEM 288 Proseminar in Bioinorganic Chemistry

Weekly meetings devoted to inorganic and bioinorganic research. Topics are drawn from current literature. Papers and reviews are discussed. Participants also give short seminars on topics of their research interests.

Credits

5

Repeatable for credit

Yes

CHEM 291 Chemistry and Biochemistry Research Seminar

A weekly chemistry and biochemistry seminar series covering recent developments and current research, led by experts from other institutions, as well as local speakers. Open to chemistry and biochemistry graduate students.

Credits

5

Requirements

Enrollment is restricted to graduate students.

Repeatable for credit

Yes

CHEM 292 Seminar

Credits

2

Requirements

Enrollment is restricted to graduate students or approval of the graduate adviser.

CHEM 296 Teaching Chemistry

University-level pedagogy in chemistry; examines the role of preparation, assessment, and feedback in teaching chemistry discussion and laboratory sections. Effective classroom techniques and organizational strategies discussed; oral presentations analyzed critically. Required of entering chemistry graduate students.

Credits

2

Requirements

Enrollment is restricted to chemistry graduate students.

CHEM 297A Independent Study

A topic will be studied with faculty tutorial assistance to satisfy a need for the student when a regular course is not available. Students submit petition to sponsoring agency.

Credits

5

Repeatable for credit

Yes

CHEM 297B Independent Study

A topic will be studied with faculty tutorial assistance to satisfy a need for the student when a regular course is not available. Students submit petition to sponsoring agency.

Credits

10

Repeatable for credit

Yes

CHEM 299A Thesis Research

Thesis Research

Credits

5

Repeatable for credit

Yes

CHEM 299B Thesis Research

Thesis Research

Credits

10

Repeatable for credit

Yes

CHEM 299C Thesis Research

Thesis Research

Credits

15

Repeatable for credit

Yes